Advance Plus combines homeopathic "drainers" with homeopathic remedies that support excretory function and address symptoms of toxicity. Cleansing itself of by-products and waste that accumulate is an essential function of the body. Homeopathic drainage, specifically, is a process of detoxifying the body that involves opening the emunctories and elimination channels and discharging toxic accumulation. Emunctories are organs of elimination: liver, kidneys, lungs, stomach, intestines, pancreas, skin, nose, and genitals. Toxic accumulation can occur from external sources, such as pesticides, insecticides, and herbicides, and from internal sources, such as stress and inadequate nutrition, which lead to undesirable changes in metabolic function.